September 6, 2010 Wrigley Field, Chicago, Illinois
Astros Record: (64-73) Cubs Record: (60-78)
W: Andrew Cashner (2-5) L: Wilton Lopez (5-2) SV: Carlos Marmol (28)
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | R | H | E | ||
| HOU | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 9 | 0 | |
| CHC | 0 | 0 | 3 | 0 | 1 | 0 | 0 | 1 | X | 5 | 9 | 1 |
| Chicago Cubs | ||||||||
| Hitters | AB | R | H | RBI | BB | SO | LOB | AVG |
| Jeff Baker, 3B | 4 | 0 | 2 | 1 | 0 | 0 | 2 | .266 |
| Blake DeWitt, 2B | 4 | 1 | 2 | 1 | 0 | 0 | 1 | .274 |
| Marlon Byrd, CF | 4 | 1 | 1 | 2 | 0 | 2 | 2 | .305 |
| Geovany Soto, C | 3 | 1 | 1 | 1 | 1 | 0 | 1 | .284 |
| Xavier Nady, 1B | 4 | 0 | 0 | 0 | 0 | 4 | 0 | .257 |
| Tyler Colvin, RF | 3 | 0 | 0 | 0 | 0 | 0 | 0 | .252 |
| Alfonso Soriano, LF | 3 | 0 | 0 | 0 | 0 | 0 | 0 | .261 |
| Darwin Barney, SS | 3 | 2 | 2 | 0 | 0 | 0 | 0 | .290 |
| Casey Coleman, P | 2 | 0 | 0 | 0 | 0 | 2 | 2 | .083 |
| Marcos Mateo, P | 0 | 0 | 0 | 0 | 0 | 0 | 0 | .000 |
| a- Welington Castillo, PH | 1 | 0 | 1 | 0 | 0 | 0 | 0 | .286 |
| Andrew Cashner, P | 0 | 0 | 0 | 0 | 0 | 0 | 0 | .000 |
| Carlos Marmol, P | 0 | 0 | 0 | 0 | 0 | 0 | 0 | .000 |
| Totals | 31 | 5 | 9 | 5 | 1 | 8 | ||
| a-singled for Mateo in the 7th | ||||||||
| Batting | ||||||||
| 2B – Jeff Baker (10, Rodriguez) | ||||||||
| HR – Marlon Byrd (12, Rodriguez), Geovany Soto (17, Lopez) | ||||||||
| RBI – Jeff Baker (19), Blake DeWitt (47), Marlon Byrd 2 (60), Geovany Soto (51) | ||||||||
| 2-OUT RBI – Blake DeWitt (22), Marlon Byrd 2 (27), Geovany Soto (18) | ||||||||
| CS – Geovany Soto (1, 2nd base by Rodriguez/Castro) | ||||||||
| Team LOB – 3 | ||||||||
| Fielding | ||||||||
| DP – Coleman-Barney-Nady, Coleman-DeWitt-Barney-Nady | ||||||||
| E – Alfonso Soriano (7, Misplayed grounder) | ||||||||
| Houston Astros | ||||||||
| Hitters | AB | R | H | RBI | BB | SO | LOB | AVG |
| Michael Bourn, CF | 3 | 1 | 2 | 0 | 2 | 0 | 0 | .258 |
| Jeff Keppinger, 2B | 4 | 0 | 1 | 1 | 0 | 0 | 1 | .285 |
| Hunter Pence, RF | 5 | 0 | 1 | 1 | 0 | 0 | 1 | .290 |
| Carlos Lee, 1B | 4 | 0 | 1 | 0 | 0 | 1 | 4 | .247 |
| Chris Johnson, 3B | 3 | 1 | 2 | 1 | 1 | 1 | 1 | .325 |
| Brian Bogusevic, LF | 4 | 0 | 0 | 0 | 0 | 2 | 3 | .167 |
| Matt Downs, SS | 2 | 1 | 1 | 0 | 1 | 0 | 0 | .250 |
| a- Anderson Hernandez, PH | 1 | 0 | 0 | 0 | 0 | 0 | 0 | .229 |
| Wilton Lopez, P | 0 | 0 | 0 | 0 | 0 | 0 | 0 | .000 |
| Jason Castro, C | 3 | 1 | 1 | 0 | 1 | 0 | 0 | .212 |
| Wandy Rodriguez, P | 3 | 0 | 0 | 0 | 0 | 0 | 4 | .196 |
| b- Geoff Blum, PH | 1 | 0 | 0 | 0 | 0 | 1 | 0 | .251 |
| Tommy Manzella, SS | 0 | 0 | 0 | 0 | 0 | 0 | 0 | .219 |
| Totals | 33 | 4 | 9 | 3 | 5 | 5 | ||
| a-grounded out for Downs in the 8th | ||||||||
| b-struck out for Rodriguez in the 8th | ||||||||
| Batting | ||||||||
| 2B – Michael Bourn (24, Coleman), Carlos Lee (26, Mateo) | ||||||||
| HR – Chris Johnson (7, Coleman) | ||||||||
| SH – Jeff Keppinger (5) | ||||||||
| RBI – Jeff Keppinger (48), Hunter Pence (80), Chris Johnson (38) | ||||||||
| 2-OUT RBI – Jeff Keppinger (26), Hunter Pence (32) | ||||||||
| SB – Michael Bourn (46, 2nd base off Coleman/Soto) | ||||||||
| Team LOB – 8 | ||||||||
| Fielding | ||||||||
| DP – Keppinger-Downs-Lee | ||||||||
| PB – Jason Castro (5) | ||||||||
| Chicago Cubs | ||||||||
| Pitchers | IP | H | R | ER | BB | SO | HR | ERA |
| Casey Coleman | 6 | 8 | 4 | 4 | 5 | 2 | 1 | 5.81 |
| Marcos Mateo | 1 | 1 | 0 | 0 | 0 | 2 | 0 | 9.49 |
| Andrew Cashner (W,2-5) | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 5.82 |
| Carlos Marmol (S,28) | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2.98 |
| Houston Astros | ||||||||
| Pitchers | IP | H | R | ER | BB | SO | HR | ERA |
| Wandy Rodriguez | 7 | 8 | 4 | 4 | 1 | 6 | 1 | 3.77 |
| Wilton Lopez (L,5-2) | 1 | 1 | 1 | 1 | 0 | 2 | 1 | 3.15 |
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